EATRIS Multi-omics Toolbox (MOTBX) – Resources for Translational Research and Multi-omics Analysis

In modern personalised medicine and translational research, multi-omics approaches—such as genomics, epigenomics, transcriptomics, proteomics, and metabolomics—play an increasingly important role. To support researchers and innovators in these complex and data-intensive analyses, the Multi-omics Toolbox (MOTBX) is available among other EATRIS training resources  MOTBX is a free online resource that brings together tools, protocols, guidelines, and other useful links in one place.

MOTBX is an open-access platform designed to accelerate translational research by making high-quality multi-omics analysis methods and resources more easily accessible not only to academic researchers but also to industry professionals and data analysts.

What is the Multi-omics Toolbox?

The Multi-omics Toolbox provides:

Protocols and best practice recommendations for various omics technologies to ensure reproducibility and comparability across studies.

Resources for quality control and quality assessment are essential for obtaining reliable and reproducible results.

Tools and guidelines for implementing FAIR principles (Findable, Accessible, Interoperable, Reusable) in data management and integration.

On the platform, resources are organised by technology groups and areas of application, such as genomics, epigenomics, transcriptomics, proteomics, and metabolomics, as well as data management and analysis. This structure enables users to find content tailored to their specific needs quickly.

Who is it for and why is it important?

MOTBX is a valuable resource for researchers working with complex datasets who wish to:

• implement standardised protocols and best practice principles;
• improve data quality and reproducibility;
• apply FAIR principles in their data management and analysis;
• more rapidly navigate the range of available tools and services.

The platform is designed as a community-driven resource, meaning that researchers are encouraged to actively contribute to its expansion, for example by submitting new links, protocols, or other useful materials.

Multi-omics approaches help to understand better the complexity of biological systems and the molecular processes that are critical for the discovery of new biomarkers, therapeutic targets, and personalised treatment solutions. At the same time, these analyses require high data quality, standardisation, and integration. The resources compiled in MOTBX help researchers to systematise processes, adhere to best practice standards, and ensure that the results obtained are reliable and reproducible.

 ☞ More information and access to MOTBX tools: https://motbx.eatris.eu/  

Information provided within the framework of the project “RSU participation in the Horizon Europe programme” (No. 1.1.1.5/3/25/I/014).

*project no. 1.1.1.5/3/25/I/014